Current biotech / bio-SWE engineering roles — each links to the company's job board (deep job-IDs expire, so links point at the board; search the role there). Colours = reachability (EU-only, no US relocation): 🟢 EU-reachable · 🟡 EU-remote / situational · 🔴 US — reference only, not reachable. updated 2026-07-27 · companies profiled in the Opportunity Catalogue · roles in the Positions Catalogue
🔴 EU-only. US roles below (on-site and US-remote, which need US work authorization) are red — reference only. Your reachable roles are all in 🟢 Apply now (20, EU-green + UK-visa-yellow, each flagged with comp or a comp: unknown tag).
🟢 Apply now — EU-reachable roles
Every reachable role in one list, ranked, each with a reachability flag and pay. Comp is shown where the posting states it or a source (levels.fyi / Glassdoor) pins it; comp: unknown means it isn't published — usually an early / equity-heavy or unstated seat, so ask at first contact. Founding / early seats are folded in here now, not a separate list. Deadlines: Pfizer UK 7/28 · Genomics England Principal Data Eng Aug 2 · AstraZeneca Sr Director Aug 9.
£110–150k base (~$180–230k total), levels.fyi · AlphaFold-scale molecular data platform, GCP/GKE/GPU. Compute-Platform variant = lowest-level systems fit. apply →
🟡Mytos — Senior SWE (Platform & Security) · London hybrid (UK-visa) · DSV/YC
comp: unknown · Go / Python / IoT — real-time hardware-data platform for automated cell manufacturing. Genuine Go role. apply →
🟡Altos Labs — Staff AI Platform Engineer · Cambridge UK hybrid (UK-visa) · ARCH/Foresite/8VC
£97.3–128k · Multi-omics + microscopy at massive scale, FAIR data platform. Sponsorship possible. apply →
comp: unknown · Infra + CI/CD + bioinformatics-pipeline productionisation for AI rare-disease discovery. apply →
🟡Relation Therapeutics — Research Data / Platform Engineer · London hybrid (UK-visa)
comp: unknown · Lab-in-the-loop AI, genomics data lakehouse. Posted recently, high confidence. apply →
🟡DNAnexus — SWE / Sr SWE · Prague · eng reqs expired — watch
comp: unknown · 125PB genomic data, 50B records/day — direct Prague/EU seat, but eng reqs currently expired (only PM live). Cold-outreach the eng leads + monitor weekly.careers →
🟢Saphetor (VarSome) — C++ / Python Engineer, variant pipeline · Remote-EU · new 2026-07-27
comp: unknown · VarSome — genome-scale variant annotation; C++ high-throughput calling pipeline + Django/DRF over 150+ data sources. Fully remote EU. apply →
Fanned across YC/startup boards, frontier-lab careers pages, platform employers, and biotech job aggregators (BioSpace, Built In, Wellfound), then fetched every apply URL to confirm it's a real, currently-open posting and cross-checked comp against the posting, levels.fyi, or Glassdoor. Entries where the posting itself states a salary that reaches $160k are 🟢; frontier labs that hide pay but credibly clear $160k (SF/Boston/London senior AI-bio seats) are 🟡 with the comp source named per row. Closed or sub-threshold roles are listed under honest gaps, not padded into the count.
🔴 US — salary stated (reference only, 9)
All US / Canada — not reachable without US relocation (you're EU-only). Kept only for the salary reference (these are real posted $160k+ bands). Your actual targets are the EU roles up top →
Pfizer — Sr. Director, Engineering Lead · 29 US locations · in-office or remote
$134k–$190k base + stock; top of band clears $160k, total comp with equity >$180k. Python/TS/React, C#/.NET, K8s, Kafka, Temporal, GCP/AWS. apply →
Frontier labs — comp estimated (12)
Mixed reachability: 🟢 Isomorphic Labs (London ×3) is EU-reachable — the real targets here; 🟡 Iambic (Boston / Bristol-UK, remote) might take a UK-remote; 🔴 Chai (SF ×3), Insitro (SF ×2), Illumina (San Diego) are US — reference only.
Chai Discovery ($13B, OpenAI/Sequoia-backed) — Software Engineer, Platform & Inference · San Francisco · onsite
~$180k–$260k est. (posting says only "highly competitive"). GPU/CUDA kernels, inference infra, Slurm/K8s. apply →
Chai Discovery — Research Engineer · San Francisco · onsite
~$200k–$300k est. Model training/eval/optimization, core model infra, PyTorch. apply →
Chai Discovery — Software Engineer, Products · San Francisco · onsite
~$170k–$240k est. Web apps, React/Vue, product engineering, Python. apply →
Isomorphic Labs ($2.1B Series B) — Senior Software Engineer, Inference Platform · London, UK · hybrid 3d
£110k–£150k base (~$180k–$230k total w/ equity), levels.fyi. GCP, GKE, NVIDIA GPUs, TPU, large-scale ML inference. apply →
~$165k–$210k est. (senior SWE, San Diego/Boston). Python, cloud security, AWS/GCP. apply →
Illumina — Senior Software Engineer (platform/cloud) · San Diego / Foster City · hybrid
$162k median, up to ~$249k–$304k senior (levels.fyi). Cloud (AWS/Azure), backend services, bioinformatics pipelines. Link is the salary reference — search live reqs on the Illumina careers site. comp ref →
🚀 Founding / early-seat context & cold-outreach
The founding / early-SWE seats are now folded into Apply now above (flagged, with comp where known). They're the portfolio backdoor — equity-heavy early roles at VC-portfolio genomics/data companies, where funds drop engineers into their NewCos, sourced from a sweep across Flagship/Foresite/ARCH, a16z/Lux/8VC, EU funds, YC/Nucleate/EF. Stack reality: most are Python/Snowflake — the pitch is “trading-grade high-throughput systems → sequencing/imaging data plane,” not a keyword match. Companies to watch live on the Watchlist.
cold-outreach founding seats (no ad yet)
🟢 EU seats, no ad yet — cold-pitch the founders: OutSee (Ahren, Cambridge, seed), Enhanc3D Genomics (OSE/CIC, UK), WhiteLab Genomics (Paris). 🔴 US — reference only (no relocation): Strand AI & Origin Bio (YC W26, SF), Betteromics (ex-Google/GRAIL), Eikon (SF, PB/week imaging — the best domain match, but US), Novaflow (SF, Founding Backend Eng, Go/K8s).
Best 5 this week (all EU-reachable): Automata London (Go+Rust, apply) · Ground Truth Labs (remote-UK) · Cradle Zürich · Isomorphic Compute Platform, London · Mytos London (Go/IoT). Then cold-pitch the EU seats above (OutSee, Enhanc3D, WhiteLab).
Honest gaps — not counted above
Surfaced in the sweep but dropped, so the count above stays clean:
Benchling — Software Engineer, Backend (Usage & Billing): role real but the specific posting is closed. Watch their careers page for the Zurich/SF backend reqs.
10x Genomics, Guardant Health, Tempus AI — comp credibly $160k+, but the sweep could not pin a single live posting URL (aggregator landing pages / bot-blocked). Go straight to their careers sites and filter "software engineer".
AbbVie Modeling/Simulation ($96.5k–$183.5k), Impiricus Lead SWE ($150k–$190k), UL Research Lead SWE ($131k–$180k) — band floor sits below $160k / midpoint under threshold. Only worth it at top-of-band.
Fastest hard-confirmed shots: Profluent (both roles, salary on the posting, $170k floor), Xaira (both, $190k floor), Freenome (remote-US, $162k floor). Frontier upside without a stated number: Chai Discovery and Isomorphic. Companies profiled in the Opportunity Catalogue →; role archetypes & strategy in the Positions Catalogue →.